Bladder Cancer in Dogs: Genetic and Environmental Risk Factors
The Internal Medicine and Oncology Services are interested in whether certain gene defects, in addition to exposure to certain environmental chemicals, contribute to the risk of bladder cancer in dogs. They are looking to obtain cheek swab samples from dogs of any breed diagnosed with bladder cancer. In addition, we have an environmental exposure questionnaire for dog owners to fill out.
Eligibility: Any dog diagnosed with transitional cell carcinoma of the bladder or urethra. Dogs can be enrolled at any time after diagnosis and may be on any treatment protocol. The inside of the dog’s cheek will be swabbed with a special brush for DNA collection (kit with brushes, instructions, owner questionnaire and free mailing provided). The swabs and environmental questionnaire will be processed by Dr. Lauren Trepanier‘s laboratory. Please contact Katherine Luethcke, DVM/PhD student, at 608-263-5520 or email@example.com with any questions or for obtaining a DNA sampling kit.
Dogs Needed For Acquired Laryngeal Paralysis Genome-Wide Association Study
The Small Animal Neurology and General Surgery Services are looking for two groups of dogs:
- PUREBRED Labrador Retrievers AND Golden Retrievers 11.5 years old or older with no history of laryngeal paralysis.
- Any breed of dog 8 years old or older that are affected with acquired laryngeal paralysis.
Having pedigree information is appreciated as study dogs should NOT be closely related to other study dogs. Enrolled dogs will receive a free clinical examination through the Small Animal Neurology or General Surgery Service at UW Veterinary Care, University of Wisconsin-Madison.
For more information please visit http://www.vetmed.wisc.edu/lab/corl/genetic-studies/ or contact firstname.lastname@example.org
This study is looking at genetic predisposition to acquired laryngeal paralysis in Labrador Retrievers and Golden Retrievers using genomic sequencing. It is supported by the Companion Animal Fund
Dogs Needed For Cruciate Rupture Genome-Wide Association Study
The Small Animal Orthopaedic Service is looking for two groups of dogs:
- PUREBRED Labrador Retrievers AND Rottweilers 8 years old or older with no history of cruciate rupture.
- PUREBRED Labrador Retrievers AND Rottweilers of any age that are affected with non-contact cranial cruciate rupture.
Having pedigree information is appreciated as study dogs should NOT be closely related to other study dogs. Enrolled dogs will receive a free clinical examination and radiographic assessment.
For more information and brochures, please visit http://www.vetmed.wisc.edu/lab/corl/canine-studies/ or email email@example.com
This study is looking at genetic predisposition to non-contact cranial cruciate rupture in Labrador Retrievers and Rottweilers using genomic sequencing. This study is supported by the Morris Animal Foundation, the Marjorie Siebert Aylen Foundation, the National Labrador Retriever Club and the AKC Canine Health Foundation.
Degenerative Suspensory Ligament Disease (DSLD) in the Horse
The Large Animal Surgery Service is looking for horses to investigating the genetic basis for degenerative suspensory ligament disease (DSLD) in the horse. We are collecting a nasal or oral tissue swab from each study horse and isolating the DNA from these samples. The DNA will be used to perform genomic genotyping of each horse. The data will be analyzed for a genetic association with the DSLD condition.
For more information please visit http://www.vetmed.wisc.edu/lab/corl/equine-studies/ or contact Dr. Sabrina Brounts (firstname.lastname@example.org).
Superficial Digital Flexor Tendon Problems and Suspensory Ligament Problems in the Horse
The Large Animal Surgery Service is looking for horses of all breeds with superficial digital flexor tendon problems or suspensory ligament problems. We are enrolling horses in two clinical trials:
- Clinical trial investigating a new ultrasound technique to aid in the rehabilitation of tendons in the horse.
- Clinical trial investigating genome-wide association with certain tendon injuries in the horse.
We will obtain the following:
- DNA sample (from nasal/oral swab or blood)
- Ultrasound examination of the affected tendon/ligament as well as the contralateral limb
For more information please visit http://www.vetmed.wisc.edu/lab/corl/equine-studies/ to determine if you horse is eligible for any of these studies, please contact Dr. Sabrina Brounts at (608)-263-7600 or email@example.com